Assay Detail
Binding
CHEMBL759682
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Inhibition of human platelet phosphodiesterase 3
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
PDE2 inhibition by the PI3 kinase inhibitor LY294002 and analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.11 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL189 | MILRINONE | 4.0 | 1 | 6.22 |
| CHEMBL98350 | LY-294002 | -1.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL189 | MILRINONE | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL98350 | LY-294002 | IC50 | = | 100000.0 | nM | 4.00 |