Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL759820

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of pepsin
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Pepsin A (CHEMBL3295)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles.
Bursavich MG, Rich DH.
J Med Chem (2002) 45 : 541 -558
PubMed 11806706 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 3 8.25 10.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3143435 1 10.00
CHEMBL3143437 1 8.82
CHEMBL3143436 1 5.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3143435 Ki = 0.1 nM 10.00
CHEMBL3143437 Ki = 1.5 nM 8.82
CHEMBL3143436 Ki = 1200.0 nM 5.92