Assay Detail
Binding
CHEMBL759962
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Inhibitory activity of compound against Plasmin was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.86 | 6.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL306448 | — | — | 1 | 6.51 |
| CHEMBL72279 | — | — | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL306448 | — | IC50 | = | 309.0 | nM | 6.51 |
| CHEMBL72279 | — | IC50 | = | 6220.0 | nM | 5.21 |