Assay Detail
Binding
CHEMBL760086
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibitory activity against human Prostaglandin G/H synthase 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and activity of sulfonamide-substituted 4,5-diaryl thiazoles as selective cyclooxygenase-2 inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.96 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17184 | — | — | 1 | 8.52 |
| CHEMBL118 | CELECOXIB | 4.0 | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17184 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL118 | CELECOXIB | IC50 | = | 40.0 | nM | 7.40 |