Assay Detail
Binding
CHEMBL760089
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Compound was tested for its inhibitory activity against recombinant human Prostaglandin G/H synthase 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N-[[(5-methyl-3-phenylisoxazol-4-yl)-phenyl]sulfonyl]propanamide, sodium salt, parecoxib sodium: A potent and selective inhibitor of COX-2 for parenteral administration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.50 | 8.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL865 | VALDECOXIB | 4.0 | 1 | 8.30 |
| CHEMBL42077 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL865 | VALDECOXIB | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL42077 | — | IC50 | = | 20000.0 | nM | 4.70 |