Assay Detail
Binding
CHEMBL760184
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition of [3H]-C18 PAF binding to human platelet membrane Platelet activating factor receptor was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of the platelet-activating factor antagonist ()-trans-2-(3-methoxy-4-phenylsulfonylethoxy-5-n-propylsulfonylphenyl)-5-(3,4,5-trimethoxyphenyl)tetrahydrofuran (L-671,284) and its analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.03 | 8.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL299944 | — | — | 1 | 8.22 |
| CHEMBL1793831 | — | — | 1 | 7.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL299944 | — | Ki | = | 6.0 | nM | 8.22 |
| CHEMBL1793831 | — | Ki | = | 14.3 | nM | 7.84 |