Assay Detail
Binding
CHEMBL760252
Review assay metadata, readout intent, target linkage, and publication context from the same page.
The compound was tested in vitro for inhibiting the 50% binding of Peroxisome proliferator activated receptor gamma
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 3. Structure-activity relationship and optimization of the N-aryl substituent.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.69 | 8.49 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL145958 | — | — | 1 | 8.49 |
| CHEMBL347076 | — | — | 1 | 7.31 |
| CHEMBL147912 | — | — | 1 | 7.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL145958 | — | Ki | = | 3.236 | nM | 8.49 |
| CHEMBL347076 | — | Ki | = | 48.98 | nM | 7.31 |
| CHEMBL147912 | — | Ki | = | 53.7 | nM | 7.27 |