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Assay Detail

CHEMBL760517

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was evaluated for the growth inhibition of P388/ADR cells.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type P388/ADR
Confidence 1 — Organism
Curated By Intermediate

Target

P388/ADR (CHEMBL614218)
Type CELL-LINE
Organism Mus musculus

Publication

N-(cyanomethyl)- and N-(2-methoxy-1-cyanoethyl)anthracyclines and related carboxyl derivatives.
Acton EM, Tong GL, Taylor DL, Streeter DG, Filppi JA, Wolgemuth RL.
J Med Chem (1986) 29 : 2074 -2079
PubMed 3761325 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL278828 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL278828 IC50 = 0.3 nM 9.52