Assay Detail
Binding
CHEMBL760823
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Phosphodiesterase 2 from bovine adrenal cortex
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Adrenal cortex |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
cGMP-dependent 3',5'-cyclic phosphodiesterase (CHEMBL3477) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Synthesis and evaluation of polycyclic pyrazolo[3,4-d]pyrimidines as PDE1 and PDE5 cGMP phosphodiesterase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137400 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137400 | — | IC50 | = | 11000.0 | nM | 4.96 |