Assay Detail
Binding
CHEMBL760861
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Inhibition of phosphorylase kinase (PhK)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Expert |
Publication
Bisindolylmaleimide inhibitors of protein kinase C. Further conformational restriction of a tertiary amine side chain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.29 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL538718 | — | — | 1 | 5.77 |
| CHEMBL26501 | RO-320432 | — | 1 | 4.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL538718 | — | IC50 | = | 1688.0 | nM | 5.77 |
| CHEMBL26501 | RO-320432 | IC50 | = | 15625.0 | nM | 4.81 |