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Assay Detail

CHEMBL760929

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of phosphodiesterase 1 (PDE1) from porcine adrenal tissue, range 20.0-34.4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

4-(3-Chloro-4-methoxybenzyl)aminophthalazines: synthesis and inhibitory activity toward phosphodiesterase 5.
Watanabe N, Adachi H, Takase Y, Ozaki H, Matsukura M, Miyazaki K, Ishibashi K, Ishihara H, Kodama K, Nishino M, Kakiki M, Kabasawa Y.
J Med Chem (2000) 43 : 2523 -2529
PubMed 10891111 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.58 4.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL545712 1 4.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL545712 IC50 = 26200.0 nM 4.58