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Assay Detail

CHEMBL761308

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Displacement of chloroquine from Fe(3+) FPIX-loaded membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

Novel short chain chloroquine analogues retain activity against chloroquine resistant K1 Plasmodium falciparum.
Stocks PA, Raynes KJ, Bray PG, Park BK, O'Neill PM, Ward SA.
J Med Chem (2002) 45 : 4975 -4983
PubMed 12408708 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.30 5.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL148195 1 5.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL148195 IC50 = 4960.0 nM 5.30