Assay Detail
Binding
CHEMBL761471
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Inhibition of Phosphodiesterase 3
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 4 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.46 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL445098 | — | — | 1 | 4.46 |
| CHEMBL50378 | EHNA | — | 1 | - |
| CHEMBL63 | ROLIPRAM | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL445098 | — | Ki | = | 35000.0 | nM | 4.46 |
| CHEMBL50378 | EHNA | Ki | > | 200000.0 | nM | - |
| CHEMBL63 | ROLIPRAM | Ki | > | 200000.0 | nM | - |