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Assay Detail

CHEMBL761555

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of guinea pig heart Phosphodiesterase 3
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Cavia porcellus
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Phosphodiesterase 3 (CHEMBL2094125)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

Preparation of the enantiomers of the novel CA-sensitizer EMD 53 998
Jonas R, Klockow M, Lues I
Bioorg Med Chem Lett (1992) 2 : 589 -592
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.30 7.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL314612 1 7.30

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL314612 IC50 = 50.0 nM 7.30