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Assay Detail

CHEMBL761685

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Compound was tested for inhibition of porcine secreted pancreatic PLA2
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Sus scrofa
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Phospholipase A2, major isoenzyme (CHEMBL4715)
Type SINGLE PROTEIN
Organism Sus scrofa

Publication

Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides.
Draheim SE, Bach NJ, Dillard RD, Berry DR, Carlson DG, Chirgadze NY, Clawson DK, Hartley LW, Johnson LM, Jones ND, McKinney ER, Mihelich ED, Olkowski JL, Schevitz RW, Smith AC, Snyder DW, Sommers CD, Wery JP.
J Med Chem (1996) 39 : 5159 -5175
PubMed 8978844 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL345986 1 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL345986 IC50 = 3.0 nM 8.52