Assay Detail
Functional
CHEMBL762009
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In vitro inhibitory concentration against chloroquine-sensitive Plasmodium falciparum; Range 3-200 nM
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Evidences for the formation of bisbenzamidine-heme complexes in cell-free systems.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL538481 | — | — | 1 | 6.70 |
| CHEMBL555095 | — | — | 1 | 6.70 |
| CHEMBL543544 | — | — | 1 | 6.70 |
| CHEMBL540380 | — | — | 1 | 6.70 |
| CHEMBL558206 | — | — | 1 | 6.70 |
| CHEMBL539512 | — | — | 1 | 6.70 |
| CHEMBL541808 | — | — | 1 | 6.70 |
| CHEMBL539612 | — | — | 1 | 6.70 |
| CHEMBL540527 | — | — | 1 | 6.70 |
| CHEMBL42338 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL538481 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL555095 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL543544 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL540380 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL558206 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL539512 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL541808 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL539612 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL540527 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL42338 | — | IC50 | = | 200.0 | nM | 6.70 |