Assay Detail
Functional
CHEMBL762032
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Inhibitory concentration required against Arachidonic acid (100 uM) induced platelet aggregatory activity
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antiplatelet activity of benzylisoquinoline derivatives oxidized by cerium(IV) ammonium nitrate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 4.21 | 4.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL25 | ASPIRIN | 4.0 | 1 | 4.46 |
| CHEMBL94365 | — | — | 1 | 4.42 |
| CHEMBL329219 | — | — | 1 | 4.29 |
| CHEMBL94954 | — | — | 1 | 4.23 |
| CHEMBL443021 | — | — | 1 | 4.18 |
| CHEMBL96602 | — | — | 1 | 4.16 |
| CHEMBL317613 | — | — | 1 | 4.11 |
| CHEMBL96407 | — | — | 1 | 4.04 |
| CHEMBL329546 | — | — | 1 | 4.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL25 | ASPIRIN | IC50 | = | 34600.0 | nM | 4.46 |
| CHEMBL94365 | — | IC50 | = | 37700.0 | nM | 4.42 |
| CHEMBL329219 | — | IC50 | = | 51300.0 | nM | 4.29 |
| CHEMBL94954 | — | IC50 | = | 59200.0 | nM | 4.23 |
| CHEMBL443021 | — | IC50 | = | 66200.0 | nM | 4.18 |
| CHEMBL96602 | — | IC50 | = | 68800.0 | nM | 4.16 |
| CHEMBL317613 | — | IC50 | = | 77100.0 | nM | 4.11 |
| CHEMBL96407 | — | IC50 | = | 90200.0 | nM | 4.04 |
| CHEMBL329546 | — | IC50 | = | 94000.0 | nM | 4.03 |