Assay Detail
Functional
CHEMBL762046
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cotransfection activity of compound against human Peroxisome proliferator activated receptor alpha was determined
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL239) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Design and synthesis of a potent and selective triazolone-based peroxisome proliferator-activated receptor alpha agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.68 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL278590 | GSK-9578 | — | 1 | 6.47 |
| CHEMBL981 | FENOFIBRIC ACID | 4.0 | 1 | 4.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL278590 | GSK-9578 | EC50 | = | 340.0 | nM | 6.47 |
| CHEMBL981 | FENOFIBRIC ACID | EC50 | = | 13000.0 | nM | 4.89 |