Assay Detail
Functional
CHEMBL762076
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Negative logarithm of growth inhibitory concentration (IC50) against human prostate carcinoma (PC-3) cell line
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.24 | 5.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL74167 | — | — | 1 | 5.96 |
| CHEMBL432721 | — | — | 1 | 5.58 |
| CHEMBL73034 | — | — | 1 | 5.27 |
| CHEMBL304619 | — | — | 1 | 5.19 |
| CHEMBL70270 | — | — | 1 | 5.06 |
| CHEMBL308603 | — | — | 1 | 4.85 |
| CHEMBL70612 | — | — | 1 | 4.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL74167 | — | IC50 | = | 1096.48 | nM | 5.96 |
| CHEMBL432721 | — | IC50 | = | 2630.27 | nM | 5.58 |
| CHEMBL73034 | — | IC50 | = | 5370.32 | nM | 5.27 |
| CHEMBL304619 | — | IC50 | = | 6456.54 | nM | 5.19 |
| CHEMBL70270 | — | IC50 | = | 8709.64 | nM | 5.06 |
| CHEMBL308603 | — | IC50 | = | 14125.38 | nM | 4.85 |
| CHEMBL70612 | — | IC50 | = | 16595.87 | nM | 4.78 |