Assay Detail

CHEMBL762198

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Inhibitory concentration against PG synthetase

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Basic antiinflammatory compounds. N,N',N''-Trisubstituted guanidines.

Rachlin S, Bramm E, Ahnfelt-Rønne I, Arrigoni-Martelli E.
J Med Chem (1980) 23 : 13 -20
PubMed 6965727 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.60	5.60

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL276368	TIMEGADINE	2.0	1	5.60

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL276368	TIMEGADINE	IC50	=	2500.0	nM	5.60