Assay Detail
Binding
CHEMBL762242
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of P450 scc
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Cholesterol side-chain cleavage enzyme, mitochondrial (CHEMBL4813) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Synthesis and evaluation of 17-aliphatic heterocycle-substituted steroidal inhibitors of 17alpha-hydroxylase/C17-20-lyase (P450 17).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL341591 | — | — | 1 | 6.00 |
| CHEMBL2111947 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL341591 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL2111947 | — | IC50 | > | 25000.0 | nM | - |