Assay Detail
Binding
CHEMBL762535
Review assay metadata, readout intent, target linkage, and publication context from the same page.
inhibition of [125I]SB 236636 binding to human PPAR gamma receptor
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Target
Peroxisome proliferator-activated receptor gamma (CHEMBL235) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Non thiazolidinedione antihyperglycaemic agents. 1: -Heteroatom substituted -phenylpropanoic acids
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 7.25 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL65805 | — | — | 1 | 9.40 |
| CHEMBL306229 | — | — | 1 | 8.60 |
| CHEMBL67948 | — | — | 1 | 7.82 |
| CHEMBL17805 | BRL-48482 | — | 1 | 7.66 |
| CHEMBL67098 | — | — | 1 | 7.48 |
| CHEMBL66767 | — | — | 1 | 7.43 |
| CHEMBL307544 | — | — | 1 | 6.22 |
| CHEMBL408 | TROGLITAZONE | 4.0 | 1 | 5.42 |
| CHEMBL70005 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL65805 | — | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL306229 | — | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL67948 | — | Ki | = | 15.0 | nM | 7.82 |
| CHEMBL17805 | BRL-48482 | Ki | = | 22.0 | nM | 7.66 |
| CHEMBL67098 | — | Ki | = | 33.0 | nM | 7.48 |
| CHEMBL66767 | — | Ki | = | 37.0 | nM | 7.43 |
| CHEMBL307544 | — | Ki | = | 600.0 | nM | 6.22 |
| CHEMBL408 | TROGLITAZONE | Ki | = | 3800.0 | nM | 5.42 |
| CHEMBL70005 | — | Ki | = | 6000.0 | nM | 5.22 |