Assay Detail
Binding
CHEMBL762802
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In vitro inhibitory concentration required against peptide deformylase (PDF)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.22 | 8.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL308333 | ACTINONIN | — | 1 | 8.82 |
| CHEMBL324693 | — | — | 1 | 5.98 |
| CHEMBL419929 | — | — | 1 | 5.08 |
| CHEMBL331367 | — | — | 1 | 5.00 |
| CHEMBL323389 | — | — | 1 | - |
| CHEMBL113143 | — | — | 1 | - |
| CHEMBL112788 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL308333 | ACTINONIN | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL324693 | — | IC50 | = | 1040.0 | nM | 5.98 |
| CHEMBL419929 | — | IC50 | = | 8390.0 | nM | 5.08 |
| CHEMBL331367 | — | IC50 | = | 9910.0 | nM | 5.00 |
| CHEMBL323389 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL113143 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL112788 | — | IC50 | > | 100000.0 | nM | - |