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Assay Detail

CHEMBL763100

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
The compound was tested for its affinity against HIV-1 protease in vitro
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Human immunodeficiency virus type 1 protease (CHEMBL243)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

HIV protease: a novel chemotherapeutic target for AIDS.
Huff JR.
J Med Chem (1991) 34 : 2305 -2314
PubMed 1875332 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.60 5.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL45627 CERULENIN 1 5.60

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL45627 CERULENIN IC50 = 2500.0 nM 5.60