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Assay Detail

CHEMBL763191

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Functional
Effective concentration which increases intracellular c-AMP production in mouse EP2- receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Prostaglandin E2 receptor EP2 subtype (CHEMBL2488)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Design and synthesis of a highly selective EP2-receptor agonist.
Tani K, Naganawa A, Ishida A, Egashira H, Sagawa K, Harada H, Ogawa M, Maruyama T, Ohuchida S, Nakai H, Kondo K, Toda M.
Bioorg Med Chem Lett (2001) 11 : 2025 -2028
PubMed 11454472 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.48 7.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL432522 1 7.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL432522 EC50 = 33.0 nM 7.48