Assay Detail
Functional
CHEMBL763264
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effective concentration which increases intracellular c-AMP production in human Prostanoid IP receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of a highly selective EP2-receptor agonist.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 6 | 7.59 | 8.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL495 | ALPROSTADIL | 4.0 | 1 | 8.74 |
| CHEMBL64663 | — | — | 1 | 7.60 |
| CHEMBL432522 | — | — | 1 | 7.43 |
| CHEMBL64804 | — | — | 1 | 6.58 |
| CHEMBL293242 | — | — | 1 | - |
| CHEMBL64423 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL495 | ALPROSTADIL | EC50 | = | 1.8 | nM | 8.74 |
| CHEMBL64663 | — | EC50 | = | 25.0 | nM | 7.60 |
| CHEMBL432522 | — | EC50 | = | 37.0 | nM | 7.43 |
| CHEMBL64804 | — | EC50 | = | 260.0 | nM | 6.58 |
| CHEMBL293242 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL64423 | — | EC50 | > | 10000.0 | nM | - |