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Assay Detail

CHEMBL763351

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of rolipram binding to PDE4
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Phosphodiesterase 4 (CHEMBL2093863)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

PDE4 inhibitors: new xanthine analogues.
Montana JG, Cooper N, Dyke HJ, Gowers L, Gregory JP, Hellewell PG, Miotla J, Morris K, Naylor R, Tuladhar B, Warneck JB.
Bioorg Med Chem Lett (1998) 8 : 2925 -2930
PubMed 9873649 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.38 7.38

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL98483 1 7.38

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL98483 IC50 = 42.0 nM 7.38