Assay Detail
Binding
CHEMBL763358
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Inhibition of Plasmodium falciparum cyclin dependent protein kinase (Pfmrk)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Plasmodium falciparum |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Design and synthesis of Pfmrk inhibitors as potential antimalarial agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.75 | 4.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL97218 | — | — | 1 | 4.75 |
| CHEMBL97264 | — | — | 1 | - |
| CHEMBL319508 | — | — | 1 | - |
| CHEMBL95917 | — | — | 1 | - |
| CHEMBL318416 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL97218 | — | IC50 | = | 18000.0 | nM | 4.75 |
| CHEMBL97264 | — | IC50 | = | 102000.0 | nM | - |
| CHEMBL319508 | — | IC50 | < | 371000.0 | nM | - |
| CHEMBL95917 | — | IC50 | = | 539000.0 | nM | - |
| CHEMBL318416 | — | IC50 | = | 187000.0 | nM | - |