Assay Detail
Binding
CHEMBL763576
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Inhibition of Phosphatidylinositol 3-kinase
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthetic studies on the furan ring of wortmannin
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 7.35 | 8.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428496 | WORTMANNIN | — | 1 | 8.38 |
| CHEMBL279160 | — | — | 1 | 7.10 |
| CHEMBL276894 | — | — | 1 | 6.57 |
| CHEMBL416892 | — | — | 1 | - |
| CHEMBL12997 | — | — | 1 | - |
| CHEMBL18596 | — | — | 1 | - |
| CHEMBL273961 | — | — | 1 | - |
| CHEMBL276384 | — | — | 1 | - |
| CHEMBL13330 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428496 | WORTMANNIN | IC50 | = | 4.2 | nM | 8.38 |
| CHEMBL279160 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL276894 | — | IC50 | = | 271.0 | nM | 6.57 |
| CHEMBL416892 | — | IC50 | >> | 500.0 | nM | - |
| CHEMBL12997 | — | IC50 | >> | 500.0 | nM | - |
| CHEMBL18596 | — | IC50 | >> | 500.0 | nM | - |
| CHEMBL273961 | — | IC50 | >> | 500.0 | nM | - |
| CHEMBL276384 | — | IC50 | >> | 500.0 | nM | - |
| CHEMBL13330 | — | IC50 | >> | 500.0 | nM | - |