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Assay Detail

CHEMBL764016

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
In vitro inhibitory activity against man plasma renin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Tissue Plasma
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Renin (CHEMBL286)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Pepstatin analogues as novel renin inhibitors.
Guégan R, Diaz J, Cazaubon C, Beaumont M, Carlet C, Clément J, Demarne H, Mellet M, Richaud JP, Segondy D.
J Med Chem (1986) 29 : 1152 -1159
PubMed 3543358 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3142766 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3142766 IC50 = 170.0 nM 6.77