Assay Detail
Binding
CHEMBL764190
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]R5020 binding to cytosolic progesterone receptor (PRc) of rat uterus
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
An efficient synthesis and biological activities of 19-nor-17-hydroxy-17-trifluoromethyl-4-estren-3-one and its analogs
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.45 | 8.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL57078 | — | — | 1 | 8.92 |
| CHEMBL1276308 | MIFEPRISTONE | 4.0 | 1 | 8.46 |
| CHEMBL301446 | — | — | 1 | 8.35 |
| CHEMBL56509 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL57078 | — | IC50 | = | 1.2 | nM | 8.92 |
| CHEMBL1276308 | MIFEPRISTONE | IC50 | = | 3.5 | nM | 8.46 |
| CHEMBL301446 | — | IC50 | = | 4.5 | nM | 8.35 |
| CHEMBL56509 | — | IC50 | = | 9.0 | nM | 8.05 |