Assay Detail
Binding
CHEMBL764348
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of secretory PLA2 activity in bee venom enzyme using [3H]oleate labelled membranes at a concentration of 10 uM
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Apis mellifera |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.09 | 5.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL89206 | — | — | 1 | 5.21 |
| CHEMBL89162 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL89206 | — | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL89162 | — | IC50 | = | 11000.0 | nM | 4.96 |