Assay Detail
Functional
CHEMBL764520
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Growth inhibitory concentration against human prostate carcinoma (PC-3) cell line
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.38 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL31400 | ELINAFIDE | 2.0 | 1 | 6.50 |
| CHEMBL74167 | — | — | 1 | 5.96 |
| CHEMBL432721 | — | — | 1 | 5.58 |
| CHEMBL73034 | — | — | 1 | 5.27 |
| CHEMBL428676 | AMONAFIDE | 3.0 | 1 | 5.20 |
| CHEMBL304619 | — | — | 1 | 5.19 |
| CHEMBL70270 | — | — | 1 | 5.06 |
| CHEMBL308603 | — | — | 1 | 4.85 |
| CHEMBL70612 | — | — | 1 | 4.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL31400 | ELINAFIDE | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL74167 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL432721 | — | IC50 | = | 2640.0 | nM | 5.58 |
| CHEMBL73034 | — | IC50 | = | 5420.0 | nM | 5.27 |
| CHEMBL428676 | AMONAFIDE | IC50 | = | 6380.0 | nM | 5.20 |
| CHEMBL304619 | — | IC50 | = | 6420.0 | nM | 5.19 |
| CHEMBL70270 | — | IC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL308603 | — | IC50 | = | 14050.0 | nM | 4.85 |
| CHEMBL70612 | — | IC50 | = | 16500.0 | nM | 4.78 |