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Assay Detail

CHEMBL764541

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of phosphodiesterase 4 at 1 uM cAMP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Phosphodiesterase 4 (CHEMBL2093863)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.
Bourguignon JJ, Désaubry L, Raboisson P, Wermuth CG, Lugnier C.
J Med Chem (1997) 40 : 1768 -1770
PubMed 9191951 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.52 5.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL445098 1 5.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL445098 IC50 = 3000.0 nM 5.52