Assay Detail
Functional
CHEMBL764657
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Tested in vitro against PC-13 human lung large cell carcinoma
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-13 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Nucleosides and nucleotides. 122. 2'-C-cyano-2'-deoxy-1-beta-D-arabinofuranosylcytosine and its derivatives. A new class of nucleoside with a broad antitumor spectrum.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.06 | 4.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1204346 | — | — | 1 | 4.06 |
| CHEMBL337389 | — | — | 1 | - |
| CHEMBL1790974 | — | — | 1 | - |
| CHEMBL803 | CYTARABINE | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1204346 | — | IC50 | = | 86800.0 | nM | 4.06 |
| CHEMBL337389 | — | IC50 | > | 360000.0 | nM | - |
| CHEMBL1790974 | — | IC50 | = | 363000.0 | nM | - |
| CHEMBL803 | CYTARABINE | IC50 | > | 410000.0 | nM | - |