Assay Detail

CHEMBL764723

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Binding affinity towards Plasmin

ChEMBL ↗

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Target

Plasminogen (CHEMBL1801) ↗

Open DB target context

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Plasminogen (CHEMBL1801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Plasminogen

CHEMBL1801

Anchored from Assay target.

Protein identity Plasminogen

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	8 — Homologous single protein target
Curated By	Autocuration

Target

Plasminogen (CHEMBL1801) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Optimization of a screening lead for factor VIIa/TF.

Young WB, Kolesnikov A, Rai R, Sprengeler PA, Leahy EM, Shrader WD, Sangalang J, Burgess-Henry J, Spencer J, Elrod K, Cregar L.
Bioorg Med Chem Lett (2001) 11 : 2253 -2256
PubMed 11527709 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	8.49	8.49

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL73737	—	—	1	8.49

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL73737	—	Ki	=	3.2	nM	8.49