Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL765008

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against HIV-1 protease.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Human immunodeficiency virus type 1 protease (CHEMBL243)
Type SINGLE PROTEIN
Organism Human immunodeficiency virus 1

Publication

Protease inhibitors: current status and future prospects.
Leung D, Abbenante G, Fairlie DP.
J Med Chem (2000) 43 : 305 -341
PubMed 10669559 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 10.51 10.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL13134 PALINAVIR 2.0 1 10.51

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL13134 PALINAVIR Ki = 0.031 nM 10.51