Assay Detail
Binding
CHEMBL765211
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In vitro inhibitory activity against recombinant human PPI using fluorescein diphosphate (FDP) as a substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and PTP1B inhibition of 1,2-naphthoquinone derivatives as potent anti-diabetic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.22 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL60707 | — | — | 1 | 5.50 |
| CHEMBL58737 | — | — | 1 | 5.09 |
| CHEMBL51447 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL60707 | — | IC50 | = | 3190.0 | nM | 5.50 |
| CHEMBL58737 | — | IC50 | = | 8060.0 | nM | 5.09 |
| CHEMBL51447 | — | IC50 | = | 8370.0 | nM | 5.08 |