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Assay Detail

CHEMBL765316

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory activity against Plasmodium berghei Ghana
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium berghei
Confidence 1 — Organism
Curated By Intermediate

Target

Plasmodium berghei (CHEMBL612653)
Type ORGANISM
Organism Plasmodium berghei

Publication

Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo.
Ghosh S, Chan JM, Lea CR, Meints GA, Lewis JC, Tovian ZS, Flessner RM, Loftus TC, Bruchhaus I, Kendrick H, Croft SL, Kemp RG, Kobayashi S, Nozaki T, Oldfield E.
J Med Chem (2004) 47 : 175 -187
PubMed 14695831 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.00 6.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL55264 1 6.30
CHEMBL54004 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL55264 IC50 = 500.0 nM 6.30
CHEMBL54004 IC50 = 2000.0 nM 5.70