Assay Detail
Binding
CHEMBL765336
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Inhibition of [3H]nitrendipine binding to dihydropyridine sites of bovine frontal cortex membranes
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Tissue | Frontal cortex |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Enantiodifferentiation of dihydropyridine PAF antagonists
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.21 | 7.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL105029 | — | — | 1 | 7.39 |
| CHEMBL53019 | — | — | 1 | 7.02 |
| CHEMBL319839 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL105029 | — | IC50 | = | 41.0 | nM | 7.39 |
| CHEMBL53019 | — | IC50 | = | 96.0 | nM | 7.02 |
| CHEMBL319839 | — | IC50 | > | 10000.0 | nM | - |