Assay Detail
Functional
CHEMBL765665
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Parasite growth inhibition against Plasmodium falciparum W2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.69 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92547 | — | — | 1 | 7.92 |
| CHEMBL2114228 | — | — | 1 | 7.75 |
| CHEMBL330260 | — | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92547 | — | IC50 | = | 12.0 | nM | 7.92 |
| CHEMBL2114228 | — | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL330260 | — | IC50 | = | 40.0 | nM | 7.40 |