Assay Detail
Binding
CHEMBL765822
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Tested for in vitro binding affinity against polyamine oxidase after intraperitoneal administration in the rat liver
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (CHEMBL3408) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Polyamine analogues with antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.63 | 5.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL417844 | — | — | 1 | 5.77 |
| CHEMBL1202500 | — | — | 1 | 5.60 |
| CHEMBL287672 | — | — | 1 | 5.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL417844 | — | Ki | = | 1700.0 | nM | 5.77 |
| CHEMBL1202500 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL287672 | — | Ki | = | 3000.0 | nM | 5.52 |