Assay Detail
Binding
CHEMBL765908
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Compound was evaluated for its concentration required to inhibit the porcine kidney F16BPase
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Allosteric inhibition of fructose-1,6-bisphosphatase by anilinoquinazolines.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.86 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL301018 | — | — | 1 | 6.47 |
| CHEMBL65250 | — | — | 1 | 6.11 |
| CHEMBL304929 | — | — | 1 | 5.80 |
| CHEMBL63676 | — | — | 1 | 5.51 |
| CHEMBL64950 | — | — | 1 | 5.41 |
| CHEMBL7917 | TYRPHOSTIN AG-1478 | — | 1 | - |
| CHEMBL35820 | — | — | 1 | - |
| CHEMBL29197 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL301018 | — | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL65250 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL304929 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL63676 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL64950 | — | IC50 | = | 3900.0 | nM | 5.41 |
| CHEMBL7917 | TYRPHOSTIN AG-1478 | IC50 | > | 10000.0 | nM | - |
| CHEMBL35820 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL29197 | — | IC50 | > | 10000.0 | nM | - |