Assay Detail
Functional
CHEMBL766038
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Parasite growth inhibition against Plasmodium falciparum F32A
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.37 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92547 | — | — | 1 | 8.10 |
| CHEMBL330261 | — | — | 1 | 7.28 |
| CHEMBL330260 | — | — | 1 | 7.24 |
| CHEMBL433008 | — | — | 1 | 7.18 |
| CHEMBL2114228 | — | — | 1 | 7.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92547 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL330261 | — | IC50 | = | 52.0 | nM | 7.28 |
| CHEMBL330260 | — | IC50 | = | 57.0 | nM | 7.24 |
| CHEMBL433008 | — | IC50 | = | 66.0 | nM | 7.18 |
| CHEMBL2114228 | — | IC50 | = | 89.0 | nM | 7.05 |