Assay Detail
Binding
CHEMBL766312
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Inhibition of human Protein kinase C delta
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Synthesis and PKC inhibitory activities of balanol analogs with a cyclopentane substructure
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 8.17 | 9.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL52529 | — | — | 1 | 9.05 |
| CHEMBL306427 | — | — | 1 | 8.40 |
| CHEMBL59828 | — | — | 1 | 8.30 |
| CHEMBL417051 | — | — | 1 | 8.30 |
| CHEMBL1794808 | — | — | 1 | 8.30 |
| CHEMBL67716 | — | — | 1 | 8.22 |
| CHEMBL421866 | — | — | 1 | 8.22 |
| CHEMBL67290 | — | — | 1 | 7.70 |
| CHEMBL431955 | — | — | 1 | 7.70 |
| CHEMBL60254 | BALANOL | — | 1 | 7.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL52529 | — | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL306427 | — | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL59828 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL417051 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL1794808 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL67716 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL421866 | — | IC50 | = | 6.0 | nM | 8.22 |
| CHEMBL67290 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL431955 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL60254 | BALANOL | IC50 | = | 30.0 | nM | 7.52 |