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Assay Detail

CHEMBL766335

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against plasmin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Expert

Target

Plasminogen (CHEMBL1801)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis, SAR and in vivo activity of novel thienopyridine sulfonamide pyrrolidinones as factor Xa inhibitors.
Becker MR, Ewing WR, Davis RS, Pauls HW, Ly C, Li A, Mason HJ, Choi-Sledeski YM, Spada AP, Chu V, Brown KD, Colussi DJ, Leadley RJ, Bentley R, Bostwick J, Kasiewski C, Morgan S.
Bioorg Med Chem Lett (1999) 9 : 2753 -2758
PubMed 10509929 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.21 5.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL92530 1 5.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL92530 Ki = 6200.0 nM 5.21