Assay Detail
Binding
CHEMBL766339
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Inhibitory activity of compound against Plasmin (HP)
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Synthesis of potent and selective inhibitors of human plasma kallikrein.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.87 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1160807 | — | — | 1 | 7.40 |
| CHEMBL1160808 | — | — | 1 | 7.22 |
| CHEMBL1160809 | — | — | 1 | 7.10 |
| CHEMBL1160813 | — | — | 1 | 6.92 |
| CHEMBL1160805 | — | — | 1 | 6.30 |
| CHEMBL1160804 | — | — | 1 | 6.25 |
| CHEMBL1160803 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1160807 | — | Ki | = | 40.0 | nM | 7.40 |
| CHEMBL1160808 | — | Ki | = | 60.0 | nM | 7.22 |
| CHEMBL1160809 | — | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL1160813 | — | Ki | = | 120.0 | nM | 6.92 |
| CHEMBL1160805 | — | Ki | = | 500.0 | nM | 6.30 |
| CHEMBL1160804 | — | Ki | = | 560.0 | nM | 6.25 |
| CHEMBL1160803 | — | Ki | = | 110000.0 | nM | - |