Assay Detail
Binding
CHEMBL766585
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Compound was tested in a functional ion channel assay of ATP-induced current at recombinant rat P2X3 receptor expressed in Xenopus oocytes.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Oocyte |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A pyridoxine cyclic phosphate and its 6-azoaryl derivative selectively potentiate and antagonize activation of P2X1 receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.16 | 4.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL304765 | — | — | 1 | 4.23 |
| CHEMBL69727 | ISOPPADS | — | 1 | 4.08 |
| CHEMBL69234 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL304765 | — | IC50 | = | 58300.0 | nM | 4.23 |
| CHEMBL69727 | ISOPPADS | IC50 | = | 83500.0 | nM | 4.08 |
| CHEMBL69234 | — | IC50 | = | 240000.0 | nM | - |