Assay Detail
Binding
CHEMBL766713
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Phosphonate derivatives of N9-benzylguanine: a new class of potent purine nucleoside phosphorylase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.21 | 7.75 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL236708 | — | — | 1 | 7.75 |
| CHEMBL285627 | — | — | 1 | 7.17 |
| CHEMBL8230 | — | — | 1 | 6.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL236708 | — | Ki | = | 18.0 | nM | 7.75 |
| CHEMBL285627 | — | Ki | = | 67.0 | nM | 7.17 |
| CHEMBL8230 | — | Ki | = | 200.0 | nM | 6.70 |