Assay Detail
Binding
CHEMBL767137
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro inhibition tested against Phospholipase A2 (HSF-PLA2) by monitoring hydrolysis of [3H]- arachidonic acid labeled Escherichia coli at 50 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Phospholipase A2, membrane associated (CHEMBL3474) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Analogs of the marine natural product scalaradial lacking the ,-unsaturated aldehyde: effects on human synovial fluid phospholipase A2 and macrophage lipid mediator production
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.30 | 4.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL56332 | — | — | 1 | 4.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL56332 | — | IC50 | = | 50000.0 | nM | 4.30 |